PET imaging of CXCR4 using copper-64 labeled peptide antagonist
نویسندگان
چکیده
منابع مشابه
PET imaging of CXCR4 using copper-64 labeled peptide antagonist
Expression of CXCR4 in cancer has been found to correlate with poor prognosis and resistance to chemotherapy. In this study we developed a derivative of the CXCR4 peptide antagonist, T140-2D, that can be labeled easily with the PET isotope copper-64, and thereby enable in vivo visualization of CXCR4 in tumors. T140 was conjugated to 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid mono ...
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ژورنال
عنوان ژورنال: Theranostics
سال: 2011
ISSN: 1838-7640
DOI: 10.7150/thno/v01p0251